Automated Microdosing System for High Pressure Reactors
Author Information
Author(s): Norbert Stoll, Ihsan Hawali, Kerstin Thurow
Primary Institution: Institute of Automation, University of Rostock
Hypothesis
The new automated dosing system can accurately handle low volumes of various chemical liquids under high pressure.
Conclusion
The new microdosing method can handle liquid dosing under high pressure with a precision of within 5%.
Supporting Evidence
- The system can dose chemical liquids in the range of 50 µL to 2.5 mL.
- It can be pressurized up to 150 bar and heated up to 200°C.
- The dosing precision was shown to be within 5% for various sample loop volumes.
- Different liquids were tested, including water, DMSO, and 1-octanol.
- The study demonstrated that larger sample loops provide better reproducibility.
- The dosing performance was affected by the viscosity of the liquids.
- The microdosing system can handle liquid volumes up to 50 µL with acceptable precision.
- The precision of dosing decreases with increasing pressure.
Takeaway
This study shows a new way to automatically measure and mix tiny amounts of liquids under high pressure, which is important for making new chemicals.
Methodology
The study involved testing different sample loop volumes and various liquids under atmospheric and high pressure to evaluate the dosing performance.
Limitations
The precision of dosing decreases with higher viscosity liquids and higher pressures.
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