Ovarian Cancer in Pregnant Women: A Study of 23 Cases
Author Information
Author(s): Behtash Nadereh, Karimi Zarchi Mojgan, Modares Gilani Mitra, Ghaemmaghami Fatemeh, Mousavi Azamsadat, Ghotbizadeh Fahimeh
Primary Institution: Vali-e-Asr Hospital, Imam Khomeini Hospital, Tehran, Iran
Hypothesis
What are the characteristics and outcomes of ovarian cancer in pregnant women?
Conclusion
Pregnant women with advanced stage ovarian cancer have a poor prognosis, while early detection can lead to better outcomes.
Supporting Evidence
- The incidence of ovarian carcinoma associated with pregnancy was found to be 0.083/1000 deliveries.
- 73.9% of patients were diagnosed in stage I and had complete remission.
- Overall survival at 5 years was 61%.
- Chemotherapy was administered to 44% of the patients, with some receiving it during pregnancy.
Takeaway
This study looked at women who had ovarian cancer while pregnant and found that if doctors catch it early, the mothers and babies can do well, but if it's found late, it can be very serious.
Methodology
Retrospective review of 23 patients with ovarian cancer diagnosed during pregnancy treated at Vali-e-Asr Hospital from 1991 to 2002.
Potential Biases
Potential referral bias as the clinic is a specialized center.
Limitations
The study is limited by its retrospective nature and small sample size.
Participant Demographics
Patients aged 20 to 40 years, median age 29.2 years.
Statistical Information
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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