Community Threat, Positive Parenting, and Accelerated Epigenetic Aging: Longitudinal Links from Childhood to Adolescence
2025

Community Threat, Positive Parenting, and Accelerated Epigenetic Aging

Sample size: 2039 publication 10 minutes Evidence: moderate

Author Information

Author(s): Metrailer Georgette, Tavares Karina, Pault Mikayla Ver, Lopez Adamari, Denherder Shane, Hernandez Valencia Everlyn, DiMarzio Karissa, Highlander April, Merrill Sarah M., Rojo-Wissar Darlynn M., Parent Justin

Primary Institution: University of Rhode Island

Hypothesis

Positive parenting practices at ages 3, 5, and 9 will buffer the detrimental effects of threat-based early life adversity on accelerated epigenetic aging in adolescence.

Conclusion

Positive parenting reduces the pace of epigenetic aging in low community-threat environments.

Supporting Evidence

  • Children exposed to early life adversity often show increased epigenetic age acceleration.
  • Positive parenting practices can mitigate the effects of environmental stressors on biological aging.
  • High levels of community threat can overwhelm the protective effects of positive parenting.

Takeaway

Kids who have supportive parents age better, especially if they don't live in scary neighborhoods.

Methodology

Data were collected from 2,039 children in the Future of Families and Child Wellbeing Study, measuring parenting practices and epigenetic aging at ages 9 and 15.

Potential Biases

The study's focus on specific demographics may limit generalizability to other racial or socioeconomic groups.

Limitations

The sample was skewed towards economically disadvantaged families and may not represent the broader population.

Participant Demographics

49.7% female, 46.7% Black, 26.5% Hispanic, 19% White non-Hispanic.

Statistical Information

P-Value

p<0.001

Confidence Interval

[0.006, 0.017]

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1101/2024.12.23.24319484

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