Internet-Based Treatment for Adults with Depressive Symptoms: Randomized Controlled Trial
2008

Internet-Based Treatment for Depression

Sample size: 263 publication 10 minutes Evidence: moderate

Author Information

Author(s): Gunther Eysenbach, Charles Spates, John Warmerdam, Lisanne Warmerdam, Annemieke van Straten, Jos Twisk, Heleen Riper, Pim Cuijpers

Primary Institution: VU University Amsterdam

Hypothesis

Is Internet-based cognitive behavioral therapy (CBT) or problem-solving therapy (PST) more effective for treating depressive symptoms compared to a waiting list control group?

Conclusion

Both Internet-based treatments are effective in reducing depressive symptoms, although the effect of PST is realized more quickly.

Supporting Evidence

  • 263 participants were randomized to three conditions: CBT, PST, and WL.
  • 70% of participants completed questionnaires after 5 weeks.
  • Effect sizes for depressive symptoms were medium for both CBT and PST.
  • 34 participants in CBT and 30 in PST showed clinically significant improvement at 12 weeks.

Takeaway

This study shows that people with depression can get better using online therapy, and one type of therapy works faster than the other.

Methodology

A 3-arm randomized controlled trial comparing Internet-based CBT, PST, and a waiting list control group.

Potential Biases

Participants were not blind to their condition, which could introduce bias.

Limitations

High attrition rates and potential selection bias due to recruitment methods.

Participant Demographics

Participants were mainly female (71%), with a mean age of 45 years, and most were from the Netherlands (92%).

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI: 0.25 - 0.84 for CBT after 8 weeks; 95% CI: 0.17 - 0.77 for PST after 5 weeks.

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.2196/jmir.1094

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