Sodium polystyrene sulfonate (Kayexalate) aspiration
2008

Sodium Polystyrene Sulfonate Aspiration Case Report

Sample size: 1 publication Evidence: low

Author Information

Author(s): Luis F Gonzalez-Cuyar, Nathaniel B Cresswell, Allen P Burke

Primary Institution: University of Maryland School of Medicine

Hypothesis

Can sodium polystyrene sulfonate aspiration lead to severe complications in terminally ill patients?

Conclusion

Sodium polystyrene sulfonate aspiration was identified as the immediate cause of death in a patient with compromised pulmonary function.

Supporting Evidence

  • Sodium polystyrene sulfonate is commonly used to treat high potassium levels in patients with renal failure.
  • The patient developed severe hypoxemia and expired shortly after oral administration of SPS.
  • Histological examination revealed extensive intraalveolar deposition of SPS crystals.

Takeaway

This report shows that a medicine used to lower potassium can cause serious problems if it gets into the lungs, especially in very sick people.

Methodology

Histological examination of lung tissue was performed post-mortem.

Limitations

The case report is based on a single patient, limiting generalizability.

Participant Demographics

A 45-year-old male with a history of HIV, Hepatitis B, and Hepatitis C.

Digital Object Identifier (DOI)

10.1186/1746-1596-3-27

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