Real-time MRI Guided Heart Procedure
Author Information
Author(s): Barbash Israel M, Saikus Christina E, Ratnayaka Kanishka, Faranesh Anthony Z, Kocaturk Ozgur, Bell Jamie A, Wu Vincent, Schenke William H, Slack Michael C, Lederman Robert J
Primary Institution: National Institute of Health, Bethesda, MD, USA
Hypothesis
Can real-time MRI guidance enable safe access and closure of the left ventricle using novel devices?
Conclusion
The study demonstrates that percutaneous transthoracic left ventricular access and closure is feasible using real-time MRI guidance and active devices.
Supporting Evidence
- Real-time MRI guidance enabled access to the LV without injuring intraventricular structures in 15 out of 16 animals.
- Three types of failure modes of the VSD occluder device were observed during follow-up.
- LV function was preserved and histology analysis indicated complete healing process around the device.
Takeaway
Doctors can use real-time MRI to safely access and close a part of the heart in pigs, which could help in future heart surgeries.
Methodology
Sixteen Yorkshire swine underwent percutaneous transthoracic LV access guided by real-time MRI, followed by closure using an occluder device.
Limitations
The study was conducted on animals, and results may not directly translate to human patients.
Participant Demographics
Yorkshire swine
Digital Object Identifier (DOI)
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