Preventing Opioid Dependence in Chronic Pain Patients
Author Information
Author(s): Clare E French, Troy David M, Dawson Sarah, Dalili Michael N, Hickman Matthew, Thomas Kyla H
Primary Institution: University of Bristol
Hypothesis
What interventions, that could be delivered in the community or primary care, are effective in secondary prevention of opioid dependence in CNCP patients on pharmaceutical opioids?
Conclusion
The study highlights the need for more high-quality research to determine the effectiveness of interventions aimed at preventing opioid dependence.
Supporting Evidence
- Of the 7102 identified reports, 18 studies were eligible for inclusion.
- Five of the seven RCTs at low risk of bias showed a positive effect on at least one relevant outcome.
- Most studies used multiple interventions or components.
Takeaway
This study looked at ways to help people with chronic pain who are taking opioids avoid becoming dependent on them. It found that more research is needed to find out what works best.
Methodology
A systematic review of randomised controlled trials and comparative non-randomised studies from high-income countries.
Potential Biases
Nine of the 10 non-randomised studies were at critical risk of bias due to lack of control for confounding.
Limitations
The conclusions are limited by the sparsity and inconsistency of available data.
Participant Demographics
Adults aged 18 and older taking prescribed opioids for chronic non-cancer pain.
Digital Object Identifier (DOI)
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