Gender difference in symptomatic radiographic knee osteoarthritis in the Knee Clinical Assessment – CAS(K): A prospective study in the general population
2008

Gender Differences in Knee Osteoarthritis

Sample size: 819 publication 10 minutes Evidence: moderate

Author Information

Author(s): Lacey Rosie J, Thomas Elaine, Duncan Rachel C, Peat George

Primary Institution: Primary Care Musculoskeletal Research Centre, Keele University

Hypothesis

What are the reasons for the observed gender difference in symptomatic radiographic knee osteoarthritis?

Conclusion

The study found that the higher occurrence of knee osteoarthritis in symptomatic males is likely due to selective non-participation bias rather than the use of comprehensive X-ray views.

Supporting Evidence

  • 745 symptomatic participants had complete X-ray data.
  • Males had a higher occurrence of knee ROA (77%) than females (61%).
  • The excess in men was particularly noted in the 65+ age group.

Takeaway

This study looked at why more men than women have knee problems. It found that fewer women showed up for the study, which might make it seem like men have more issues.

Methodology

A community-based prospective study involving 819 adults aged ≥50 years reporting knee pain, assessed through questionnaires and X-ray imaging.

Potential Biases

There is a risk of selective non-participation bias, particularly among symptomatic older women.

Limitations

The study did not collect data on sports and recreational activities, which are risk factors for knee OA, and the participants may not be representative of the UK population.

Participant Demographics

Participants were adults aged ≥50 years, with a mean age of 65.2 years and a mean BMI of 29.6 kg/m².

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI: 3.6%, 23.8%

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2474-9-82

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