Prevention of Vitamin D deficiency in infancy: daily 400 IU vitamin D is sufficient
2011

Daily 400 IU Vitamin D is Sufficient to Prevent Deficiency in Infants

Sample size: 85 publication Evidence: moderate

Author Information

Author(s): Mutlu Gul Yesiltepe, Kusdal Yusuf, Ozsu Elif, Cizmecioglu Filiz M, Hatun Sukru

Primary Institution: Kocaeli University, Kocaeli, Turkey

Hypothesis

Is daily supplementation of 400 IU vitamin D sufficient to prevent vitamin D deficiency in infants?

Conclusion

The study concludes that 400 IU/day vitamin D is adequate to prevent vitamin D deficiency in infants.

Supporting Evidence

  • 90% of infants received the recommended 400 IU of vitamin D daily.
  • 10% of subjects had serum 25-OH-D levels lower than 20 ng/ml.
  • Among infants older than 12 months, only 20% continued vitamin D supplementation.
  • Subjects with adequate compliance had sufficient 25-OH-D levels.

Takeaway

Giving babies 400 IU of vitamin D every day helps keep them healthy and prevents a disease called rickets.

Methodology

The study evaluated 85 infants' vitamin D status who were part of a national screening program, measuring their serum vitamin D levels after providing them with daily vitamin D supplementation.

Potential Biases

There may be bias in self-reported compliance from mothers.

Limitations

The study did not consider the infants' nutrition style and sun exposure.

Participant Demographics

The study included 85 healthy infants, with 45 girls and 40 boys, mean age of 263 days.

Statistical Information

P-Value

0.00

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1687-9856-2011-4

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