Towards systems genetic analyses in barley: Integration of phenotypic, expression and genotype data into GeneNetwork
2008

Integrating Barley Data into GeneNetwork

Sample size: 150 publication Evidence: moderate

Author Information

Author(s): Arnis Druka, Ilze Druka, Arthur G Centeno, Hongqiang Li, Zhaohui Sun, William T Thomas, Nicola Bonar, Brian J Steffenson, Steven E Ullrich, Andris Kleinhofs, Roger P Wise, Timothy J Close, Elena Potokina, Zewei Luo, Carola Wagner, Günther F Schweizer, David F Marshall, Michael J Kearsey, Robert W Williams, Robbie Waugh

Primary Institution: Scottish Crop Research Institute

Hypothesis

Can integrating phenotypic, expression, and genotype data improve genetic analysis in barley?

Conclusion

The integration of barley genotypic, phenotypic, and mRNA abundance data sets into GeneNetwork provides accessible data for the research community.

Supporting Evidence

  • The study generated novel phenotypic, mRNA abundance, and SNP-based genotyping data sets.
  • GeneNetwork allows users to test genetic hypotheses about trait interactions.
  • The integration of datasets enhances the potential for identifying gene targets.

Takeaway

This study helps scientists understand barley better by putting different types of data together in one place, making it easier to find important information.

Methodology

Data from 150 recombinant doubled haploid barley lines were integrated into GeneNetwork for analysis.

Limitations

The study relies on data from an unsequenced crop plant, which may limit some analyses.

Participant Demographics

The barley lines used were derived from a cross between two cultivars, Steptoe and Morex.

Digital Object Identifier (DOI)

10.1186/1471-2156-9-73

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