SCUD: Saccharomyces Cerevisiae Ubiquitination Database
Author Information
Author(s): Lee Won-Chul, Lee Minho, Jung Jin Woo, Kim Kwang Pyo, Kim Dongsup
Primary Institution: Korea Advanced Institute of Science and Technology
Conclusion
The SCUD database provides a comprehensive representation of the ubiquitination system in yeast and is designed to be easily expandable with further experimental data.
Supporting Evidence
- SCUD includes information on 1 E1, 11 E2, 42 E3, and 20 deubiquitination enzymes.
- A total of 940 ubiquitinated substrates, including mutant and synthetic substrates, were identified.
- The database allows users to examine various ubiquitination features such as site, type, and effect.
Takeaway
SCUD is a website that helps scientists find information about how proteins in yeast are modified by a process called ubiquitination, which is important for many biological functions.
Methodology
The database was constructed by searching for known ubiquitination enzymes and substrates through literature and organizing them into classes and subclasses.
Limitations
The database may not include all previously identified substrates and relies on literature searches for data collection.
Digital Object Identifier (DOI)
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