Efficacy of Intramuscular Dexketoprofen for Postoperative Pain Management
Author Information
Author(s): P. T. Jamdade, A. Porwal, J. V. Shinde, S. S. Erram, V. V. Kamat, P. S. Karmarkar, K. Bhagtani, S. Dhorepatil, R. Irpatgire, H. Bhagat, S. S. Kolte, P. A. Shirure
Primary Institution: Dr. Shankarrao Chavan Government Medical College & Hospital, Nanded, Maharashtra, India
Hypothesis
To evaluate the safety and efficacy of intramuscular dexketoprofen for postoperative pain in patients undergoing hernia surgery.
Conclusion
Dexketoprofen provided faster, better, and longer-lasting pain relief than diclofenac in patients after hernia repair surgery.
Supporting Evidence
- Dexketoprofen showed superior efficacy in terms of number of responders.
- The onset of analgesia for dexketoprofen was significantly faster than diclofenac.
- The duration of analgesia for dexketoprofen was significantly greater than diclofenac.
- Adverse events were comparable between dexketoprofen and diclofenac groups.
Takeaway
This study shows that a single shot of dexketoprofen helps people feel less pain after hernia surgery faster and for a longer time than another medicine called diclofenac.
Methodology
202 patients received either dexketoprofen or diclofenac postoperatively, and pain was measured using a visual analogue scale at various time points.
Potential Biases
Potential bias due to the open-label design.
Limitations
The study was open-label, which may introduce bias.
Participant Demographics
Patients aged 18–65 years undergoing hernia surgery, with a mix of genders.
Statistical Information
P-Value
.007
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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