Assessment of efficacy and impact on work productivity and attendance after a mandatory switch to generic second-generation antihistamines: results of a patient survey in Norway
2011

Impact of Switching to Generic Antihistamines in Norway

Sample size: 409 publication Evidence: moderate

Author Information

Author(s): Thorn Fredrik, Celius Halvor, Ødegård Tone, Mandla Randeep, Hexeberg Erik

Primary Institution: Nordstrand Legesenter, Oslo, Norway

Hypothesis

How does switching from branded to generic antihistamines affect patient outcomes?

Conclusion

The mandated switch to generic antihistamines led to decreased symptom control and work productivity among patients.

Supporting Evidence

  • 46.3% of respondents rated the new medications as less effective.
  • 28.7% reported increased fatigue after switching.
  • 31.6% experienced decreased work productivity with the new medications.
  • 26% of respondents switched back to their previous medication.

Takeaway

When patients switched to cheaper allergy medicines, many felt they didn't work as well and had more tiredness, which made it harder for them to work.

Methodology

Patients completed a 25-item online survey assessing their experiences after switching medications.

Potential Biases

Responses were only from patients who had to switch medications, which may skew results.

Limitations

There was no control group, and results may not apply to all allergy patients.

Participant Demographics

{"sex_distribution":{"female":66.3,"male":33.7},"age_distribution":{"18-25":35,"26-35":67,"36-45":101,"46-55":122,"56-65":84},"diagnosis_distribution":{"pollen_allergy":63.7,"other_nasal_allergy":15.2,"skin_allergy":6.9,"other":14.3}}

Digital Object Identifier (DOI)

10.1186/1476-7961-9-5

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