Efficacy and safety of red ginseng extract powder (KGC05pg) in achieving glycemic control in prediabetic Korean adults: A 12-week, single-center, randomized, double-blind, parallel-group, placebo-controlled study
2024

Red Ginseng Extract for Blood Sugar Control in Prediabetic Adults

Sample size: 98 publication 10 minutes Evidence: moderate

Author Information

Author(s): Jeong Yoonseon, Lee Seung Ho, Shim Sung Lye, Jang Kyoung Hwa, Kim Jong Han

Primary Institution: Korea Ginseng Corporation Research Institute

Hypothesis

This study aims to assess the efficacy and safety of Red Ginseng Extract Powder (RGEP) in achieving glycemic control in prediabetic Korean adults.

Conclusion

RGEP might be effective in achieving glycemic control in prediabetic Korean adults.

Supporting Evidence

  • There were significant differences in fasting blood glucose and other glycemic control parameters between the RGEP and placebo groups.
  • RGEP showed a significant time-dependent decrease in dipeptidyl peptidase-4 levels.
  • There were no treatment-emergent adverse events reported in either treatment arm.

Takeaway

This study tested a ginseng supplement to see if it helps people who are at risk of diabetes control their blood sugar better.

Methodology

A 12-week, single-center, randomized, double-blind, parallel-group, placebo-controlled study with 98 participants divided into RGEP and placebo groups.

Potential Biases

Selection bias could not be completely ruled out due to the single-center design.

Limitations

The study is small-scale and single-center, which may limit the generalizability of the results.

Participant Demographics

Korean adults aged 19 and older with prediabetes.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1097/MD.0000000000041130

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