Antidepressant Use in Pregnant Women
Author Information
Author(s): É Ramos, D Oraichi, É Rey, L Blais, A Bérard
Primary Institution: Research Center, CHU Sainte-Justine Hospital
Hypothesis
What is the prevalence and what factors predict antidepressant use before, during, and after pregnancy?
Conclusion
Antidepressant use declines significantly once pregnancy is diagnosed.
Supporting Evidence
- Antidepressant use was 6.6% before pregnancy and dropped to 3.7% during the first trimester.
- Women on welfare were more likely to use antidepressants.
- Older maternal age was associated with higher antidepressant use.
Takeaway
This study found that many women stop taking antidepressants when they become pregnant, which might not be good for their health.
Methodology
The study used a retrospective longitudinal cohort design, analyzing data from three administrative databases in Quebec.
Potential Biases
Potential misclassification of planned abortions and miscarriages could affect results.
Limitations
The study may not include women who do not use medical services during pregnancy or those who give birth outside of hospitals.
Participant Demographics
Women aged 15-45 years, primarily urban dwellers, with a mean age of 27.4 years.
Statistical Information
P-Value
p<0.01
Confidence Interval
95% CI
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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