Laparoscopic and Endoscopic cooperative surgery as Rescue-treatment for Advanced gastric Cancer in patients Unfit for Surgery (LE-RACUS): protocol for a feasibility study
2025

Feasibility Study of Laparoscopic and Endoscopic Cooperative Surgery for Advanced Gastric Cancer

Sample size: 15 publication Evidence: low

Author Information

Author(s): Maltzman Henrik, Omae Masami, Klevebro Fredrik, Baldaque-Silva Francisco, Rouvelas Ioannis

Primary Institution: Karolinska University Hospital, Sweden

Hypothesis

Can Laparoscopic and Endoscopic Cooperative Surgery (LECS) be a safe treatment option for patients with advanced gastric cancer who are unfit for traditional surgery?

Conclusion

LECS is a promising, less invasive treatment option for patients with advanced gastric cancer who cannot tolerate gastrectomy.

Supporting Evidence

  • LECS is primarily used in Asian countries for gastrointestinal stromal tumors.
  • LECS has a documented low complication rate compared to traditional surgery.
  • No previous prospective studies have evaluated LECS for advanced gastric cancer.

Takeaway

This study is trying to see if a new, less invasive surgery can help older patients with stomach cancer who can't have regular surgery.

Methodology

The study will be a single-center, prospective feasibility trial assessing the safety of LECS in patients with advanced gastric cancer.

Limitations

Patient inclusion may be challenging due to strict criteria and the low incidence of gastric cancer in Sweden.

Participant Demographics

Patients with advanced gastric cancer who are unfit for gastrectomy, primarily elderly individuals.

Digital Object Identifier (DOI)

10.1186/s40814-024-01584-3

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