Oral contraceptives and breast cancer: latest findings in a large cohort study
1989

Oral Contraceptives and Breast Cancer: Latest Findings

Sample size: 17032 publication Evidence: high

Author Information

Author(s): M.P. Vessey, K. McPherson, L. Villard-Mackintosh, D. Yeates

Primary Institution: Department of Community Medicine and General Practice, Radcliffe Infirmary, Oxford, UK

Hypothesis

Does the use of oral contraceptives increase the risk of breast cancer in women aged 25-39?

Conclusion

The study found no evidence that oral contraceptive use increases breast cancer risk in mature women.

Supporting Evidence

  • The study followed 17,032 women over several years.
  • 189 cases of breast cancer were diagnosed among the participants.
  • Previous studies have shown no adverse effect of oral contraceptives on breast cancer risk.

Takeaway

This study looked at a lot of women to see if taking the pill makes them more likely to get breast cancer, and it found that it doesn't.

Methodology

The study analyzed breast cancer incidence rates among users and non-users of oral contraceptives and conducted case-control analyses.

Limitations

The study had little exposure to the pill before first term pregnancy and virtually none at a very young age.

Participant Demographics

Women aged 25-39, primarily white British, recruited from family planning clinics.

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