Levocabastine Eye Drops for Allergic Conjunctivitis in Children
Author Information
Author(s): Brunello WLithrich, Martin Gerber
Primary Institution: University Hospital, Zürich, Switzerland
Hypothesis
Levocabastine eye drops are effective and well tolerated for the treatment of seasonal allergic conjunctivitis in children.
Conclusion
Levocabastine eye drops are effective and well tolerated for treating seasonal allergic conjunctivitis in children.
Supporting Evidence
- Total severity of ocular symptoms decreased by 84% in patients under 12 years and 85% in those over 12 years.
- Treatment tolerability was considered excellent or good by 94% of patients overall.
- Global assessments revealed that 81% of patients under 12 years and 82% of those over 12 years rated the therapy as excellent or good after 2 weeks.
Takeaway
This study shows that a medicine called levocabastine helps kids with eye allergies feel better and is safe to use.
Methodology
This was an open-label, prospective, multicentre trial conducted over 4 weeks with children aged 5 to 16 years who had seasonal allergic conjunctivitis.
Limitations
Some patients were excluded from the efficacy analysis due to insufficient symptom severity or non-compliance.
Participant Demographics
The study included 177 children (103 boys, 54 girls) and 56 adolescents (32 boys, 17 girls) aged 5 to 16 years.
Statistical Information
P-Value
p < 0.001
Statistical Significance
p<0.01
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