Literacy and recent history of diarrhoea are predictive of Plasmodium falciparum parasitaemia in Kenyan adults
2006

Literacy and Diarrhoea Predict Malaria in Kenyan Adults

Sample size: 1141 publication 10 minutes Evidence: moderate

Author Information

Author(s): Rodney L Coldren, Trish Prosser, Fredrick Ogolla, Victor O Ofula, Nicholas Adungo

Primary Institution: United States Army Medical Research Unit – Kenya

Hypothesis

Are literacy and recent history of diarrhoea predictive of Plasmodium falciparum parasitaemia in Kenyan adults?

Conclusion

District of residence, literacy, and recent diarrhoeal illness are significant predictors of malaria parasitaemia among Kenyan adults.

Supporting Evidence

  • 1,141 subjects were recruited from three districts in Kenya.
  • Parasitaemia rates were significantly different across districts.
  • Literate individuals had higher rates of parasitaemia compared to illiterate individuals.
  • Recent diarrhoeal illness was associated with increased parasitaemia rates.

Takeaway

This study found that being able to read and having diarrhoea recently can increase the chances of having malaria in Kenyan adults.

Methodology

A population-based, cross-sectional study was conducted using a two-stage cluster sampling technique to enroll consenting adults from selected villages.

Potential Biases

Potential bias from self-reported health histories and antimalarial usage.

Limitations

Self-reported data may introduce bias, and the study's design limits the ability to generalize findings beyond the selected districts.

Participant Demographics

The study included 1141 adults, with 64.1% female and 35.9% male participants.

Statistical Information

P-Value

p = 0.023 for literacy, p = 0.067 for diarrhoeal illness

Confidence Interval

95% CI for adjusted relative odds reported in the results

Statistical Significance

p < 0.001

Digital Object Identifier (DOI)

10.1186/1475-2875-5-96

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