Outcomes of Ascitic Fluid Infections in Cirrhotic Patients
Author Information
Author(s): Kamani Lubna, Mumtaz Khalid, Ahmed Umair S, Ali Ailia W, Jafri Wasim
Primary Institution: Aga Khan University Hospital
Hypothesis
The study aims to determine the outcomes in cirrhotic patients with culture positive and culture negative ascitic fluid infections.
Conclusion
Patients with spontaneous bacterial peritonitis (SBP) have a higher mortality rate than those with culture negative neutrocytic ascites (CNNA).
Supporting Evidence
- 44 out of 187 patients had spontaneous bacterial peritonitis (SBP).
- Patients with SBP had a higher Child Turcotte Pugh score compared to those with CNNA.
- The mortality rate was 25% in the SBP group compared to 8.4% in the CNNA group.
Takeaway
This study looked at patients with liver disease who had infections in their abdominal fluid. It found that those with one type of infection had a higher chance of dying than those with another type.
Methodology
The study analyzed 675 patients with hepatitis B and/or C related cirrhosis and ascites, focusing on those with ascitic fluid infections.
Limitations
The study excluded patients with secondary bacterial peritonitis and those who had received antibiotics within 30 days.
Participant Demographics
Patients were primarily those with hepatitis B and/or C related cirrhosis, with a mean age of around 52 years.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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