Malaria Morbidity in Papua Indonesia
Author Information
Author(s): Karyana Muhammad, Burdarm Lenny, Yeung Shunmay, Kenangalem Enny, Wariker Noah, Maristela Rilia, Umana Ketut Gde, Vemuri Ram, Okoseray Maurits J, Penttinen Pasi M, Ebsworth Peter, Sugiarto Paulus, Anstey Nicholas M, Tjitra Emiliana, Price Richard N
Primary Institution: National Institute of Health Research and Development, Ministry of Health, Jakarta, Indonesia
Hypothesis
The study aims to document the epidemiology of malaria in Papua, Indonesia, particularly focusing on multidrug-resistant Plasmodium vivax and Plasmodium falciparum.
Conclusion
Both P. vivax and P. falciparum are associated with significant morbidity in Papua, with P. vivax predominating in infants and symptomatic infections reducing with age.
Supporting Evidence
- The study reported 99,158 laboratory-confirmed episodes of malaria over two years.
- 58% of cases were due to P. falciparum and 37% to P. vivax.
- Malaria prevalence was highest in children under one year of age.
- The overall incidence of malaria was estimated at 876 per 1,000 per year.
Takeaway
In Papua, many kids get sick from malaria, especially from a type called P. vivax, and it's important to know how many people are affected to help them better.
Methodology
The study reviewed laboratory-confirmed malaria cases and conducted a household survey to assess malaria prevalence and treatment-seeking behavior.
Potential Biases
Potential bias in treatment-seeking behavior and underreporting of malaria cases.
Limitations
The study may not capture all malaria cases due to underreporting and reliance on health facility data.
Participant Demographics
The study included 5,255 participants, with a median age of 21 years, and a diverse ethnic composition including highland Papuans, lowland Papuans, and non-Papuans.
Statistical Information
P-Value
p<0.05
Confidence Interval
95% CI
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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