Herpes Simplex Encephalitis with Normal CSF Analysis
Author Information
Author(s): Gkrania-Klotsas Effrossyni, Lever Andrew ML
Primary Institution: Addenbrooke's Hospital, University of Cambridge Teaching Hospital NHS Trust
Conclusion
Herpes simplex encephalitis can present with brain hemorrhage and normal cerebrospinal fluid analysis, highlighting the need for clinical awareness.
Supporting Evidence
- Herpes simplex encephalitis can be fatal if not treated promptly.
- New diagnostic techniques are improving the identification of herpes simplex encephalitis.
- Normal cerebrospinal fluid analysis does not rule out herpes simplex encephalitis.
Takeaway
Sometimes, a brain infection called herpes simplex encephalitis can happen even if tests on the fluid around the brain look normal. It's important for doctors to be aware of this.
Methodology
The diagnosis was made using cerebrospinal fluid polymerase chain reaction for herpes simplex virus.
Limitations
The case is based on a single patient, which may limit generalizability.
Participant Demographics
A 46-year-old heterosexual male with no significant past medical history.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website