ProtRepeatsDB: A Database of Amino Acid Repeats in Genomes
Author Information
Author(s): Kalita Mridul K, Ramasamy Gowthaman, Duraisamy Sekhar, Chauhan Virander S, Gupta Dinesh
Primary Institution: International Centre for Genetic Engineering and Biotechnology (ICGEB)
Conclusion
ProtRepeatsDB is a multi-organism database that facilitates the identification and comparative analysis of amino acid repeats in proteins.
Supporting Evidence
- The database contains 120,686 perfect repeats and 834,621 mismatch repeats from 894,890 protein sequences.
- It provides tools for genome-wide queries and cross-species comparisons of amino acid repeats.
- The database is the first of its kind to integrate various types of amino acid repeats.
Takeaway
This study created a database that helps scientists find and compare repeating patterns in proteins from different organisms.
Methodology
The database was constructed using scripts to automate sequence retrieval and various repeat-finding algorithms, storing results in a MySQL database.
Limitations
The database may contain unverified sequences from RefSeq genomes, which could affect the accuracy of the data.
Digital Object Identifier (DOI)
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