Study of Group A Streptococcus Types in India
Author Information
Author(s): Sagar Vivek, Kumar Rajesh, Ganguly Nirmal K, Chakraborti Anuradha
Primary Institution: Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
Hypothesis
What is the comparative distribution of emm types in throat versus skin isolates of Group A Streptococcus in India?
Conclusion
The study found no significant association between emm type and the source of isolation, despite the diversity in emm type patterns.
Supporting Evidence
- 37 different emm types were identified among the 94 isolates analyzed.
- The most frequently observed emm types were emm49 and emm112.
- Six emm1-2 isolates were found to be positive for the crs gene.
- Only eleven emm types were found to be common in both throat and skin isolates.
Takeaway
Researchers looked at different types of bacteria that cause throat and skin infections in India and found that they are quite different, but it doesn't matter where they come from.
Methodology
The study analyzed 94 isolates of Group A Streptococcus from throat and skin samples, identifying 37 different emm types and screening for the crs gene.
Limitations
The study involved a small sampling of isolates from one area of a highly diverse country.
Participant Demographics
Isolates were collected from patients with throat and skin infections in India, primarily children aged 5-15 years.
Digital Object Identifier (DOI)
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