Malaria incidence in Limpopo Province, South Africa, 1998–2007
2008

Malaria Incidence in Limpopo Province, South Africa (1998–2007)

Sample size: 58768 publication 10 minutes Evidence: high

Author Information

Author(s): Annette A. M. Gerritsen, Philip Kruger, Maarten F. Schim van der Loeff, Martin P. Grobusch

Primary Institution: Department of Public Health, University of Venda

Hypothesis

The study aims to provide an overview of malaria incidence and mortality in Limpopo Province and detect trends over time.

Conclusion

There was a significant decreasing trend in malaria incidence in Limpopo Province from 1998 to 2007.

Supporting Evidence

  • A total of 58,768 malaria cases were reported during the study period.
  • The mean incidence rate was 124.5 per 100,000 person-years.
  • The incidence rate decreased from 173.0 in 1998–1999 to 50.9 in 2006–2007.
  • The case fatality rate (CFR) was stable at 1.1% over the study period.
  • The incidence rate was highest in males at 145.8 per 100,000 person-years.

Takeaway

This study looked at how many people got malaria in Limpopo Province over several years and found that fewer people got sick over time.

Methodology

The study used routinely collected data on diagnosed malaria cases and deaths from the provincial malaria information system and analyzed trends using Chi squared tests.

Potential Biases

Potential underreporting of cases due to reliance on passive surveillance.

Limitations

The study relies on routine data which may have underreporting and does not account for migrants in population estimates.

Participant Demographics

The median age of cases was 21 years, with a higher incidence in males (55%) compared to females (45%).

Statistical Information

P-Value

p < 0.001

Confidence Interval

95% CI

Statistical Significance

p < 0.001

Digital Object Identifier (DOI)

10.1186/1475-2875-7-162

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