Risk Factors of Anemia After Kidney Transplant in Sudan
Author Information
Author(s): Banaga Amin SI, Yousif Mohamed EA, Elmusharaf Khalifa
Primary Institution: University of Medical Sciences and Technology
Hypothesis
What are the prevalence and risk factors of post-transplant anemia among Sudanese kidney transplant recipients?
Conclusion
Late post-transplant anemia is common among Sudanese kidney transplant patients, with renal dysfunction and not using EPO before transplantation being major risk factors.
Supporting Evidence
- 39.5% of the patients were found to be anaemic.
- Renal dysfunction and not using EPO in the pre-transplant period were identified as major predictors of late PTA.
- History of rejection and longer duration since transplantation were also associated with increased risk of anemia.
Takeaway
Many people who get a kidney transplant in Sudan have anemia, which means they don't have enough healthy red blood cells. This can happen if they didn't get a medicine called EPO before their transplant or if their kidneys aren't working well.
Methodology
This was a cross-sectional study involving 114 kidney transplant recipients at three hospitals in Sudan, collecting clinical and laboratory data.
Potential Biases
Financial constraints may have affected the management of anemia and the use of EPO in the pre-transplant period.
Limitations
The study lacked data on iron stores and serum albumin, and detailed medical histories of co-morbidities were difficult to obtain.
Participant Demographics
68% male, mean age 42 years, 71.1% unemployed, 86.8% received kidneys from living related donors.
Statistical Information
P-Value
< 0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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