Link Between Inflammation Index and Gallstones in Women
Author Information
Author(s): Liu Bailiang, Jin Luyuan, Nan Boyuan, Sun Zhongyi, Chen Fengyang, Zhou Yinghui, Sa Qila, Feng Yingnan, Men Ao, Wang Wenxin, Feng Xiaodong, Zhang Wei
Primary Institution: General Hospital of Northern Theater Command, Shenyang, China
Hypothesis
Is there a relationship between the Advanced Lung Cancer Inflammation Index (ALI) and the prevalence of gallstones in US adults?
Conclusion
The study found a positive correlation between ALI and gallstones, particularly affecting women more significantly.
Supporting Evidence
- Gallstone prevalence increased by 45% in the highest ALI quartile compared to the lowest.
- ALI was positively correlated with gallstones with an odds ratio of 1.22.
- Significant gender differences were found, with a stronger association in women.
Takeaway
This study shows that higher inflammation levels can lead to more gallstones, especially in women.
Methodology
Cross-sectional study using NHANES data, analyzed with logistic regression and subgroup analysis.
Potential Biases
Potential confounding factors not fully controlled, such as genetics and other health conditions.
Limitations
The study is cross-sectional, limiting causal inference, and relies on self-reported data for gallstone diagnosis.
Participant Demographics
Average age 50.43 years, 50.21% male, 49.79% female.
Statistical Information
P-Value
0.005
Confidence Interval
95% CI: 1.12–1.87
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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