Effect of case management on viral load in adult clients enrolled due to non-suppression in Capricorn District, South Africa: A case control study
2025

Impact of Case Management on Viral Load in HIV Patients

Sample size: 3256 publication 10 minutes Evidence: moderate

Author Information

Author(s): Moholola Molebatsi, Rees Kate, Motsoane Nthabiseng, Kgopong Ntsetse, Mutyambizi Chipo

Primary Institution: Anova Health Institute

Hypothesis

Does case management improve viral load suppression in HIV patients with non-suppression?

Conclusion

Case management significantly improved viral load suppression among clients in Capricorn District, but many clients remained unsuppressed.

Supporting Evidence

  • 49% of clients receiving case management achieved a viral load below 50 copies/ml.
  • Case management was associated with a 25% increase in the odds of viral suppression.
  • Older age groups had higher odds of viral suppression compared to younger groups.
  • Being male was associated with lower odds of viral suppression.

Takeaway

This study found that helping people with HIV stick to their treatment can lower the amount of virus in their blood, but many still need more help.

Methodology

A case control study comparing clients receiving case management with those not receiving it, using logistic regression analysis.

Potential Biases

Data quality issues and missing data may affect the results.

Limitations

The study is not nationally representative and only includes adults, limiting generalizability.

Participant Demographics

69% female, 57% aged 35-54 years, and 61% on ART for 3-10 years.

Statistical Information

P-Value

0.00

Confidence Interval

1.08–1.44

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0317015

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