Abnormal Glucose Metabolism in Atrial Fibrillation Among 75-Year-Olds
Author Information
Author(s): Johansen Odd Erik, Brustad Ellen, Enger Steve, Tveit Arnljot
Primary Institution: Asker and Baerum Hospital
Hypothesis
Is there a prevalence of undiagnosed dysglycaemia among subjects with atrial fibrillation compared to those without?
Conclusion
Atrial fibrillation is linked to higher rates of chronic hyperglycaemia in older adults, especially if the duration of AF is five years or more.
Supporting Evidence
- 3.7% of subjects without AF had undiagnosed diabetes compared to 13.0% with AF.
- The prevalence of dysglycaemia was similar between groups, but higher in those with AF duration ≥ 5 years.
- There was a significant correlation between AF duration and HbA1c levels.
Takeaway
Older people with atrial fibrillation might have high blood sugar levels, especially if they've had it for a long time.
Methodology
A case-control study assessing glucose metabolism using a 75-g oral glucose tolerance test among 75-year-old subjects with and without atrial fibrillation.
Potential Biases
Differences in vascular co-morbidity between groups may affect the interpretation of results.
Limitations
The study had a relatively small sample size and only included 75-year-old subjects.
Participant Demographics
75-year-old subjects, 34 males and 12 females with AF, and 73 males and 35 females without AF.
Statistical Information
P-Value
0.031
Confidence Interval
[95% CI: 1.01, 16.25]
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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