Prevalence and Clinical Pattern of Pediatric HIV Infection in Nigeria
Author Information
Author(s): Ogunbosi Babatunde O, Oladokun Regina E, Brown Biobele J, Osinusi Kikelomo I
Primary Institution: University College Hospital, Ibadan, Nigeria
Hypothesis
What is the prevalence and clinical pattern of HIV infection among children under 15 years in Nigeria?
Conclusion
The study found a high prevalence of HIV infection among new patients, primarily due to mother-to-child transmission, with many children presenting in advanced stages of the disease.
Supporting Evidence
- HIV seroprevalence was found to be 12.3%, with a confirmed prevalence of 10%.
- 93.3% of cases were due to mother-to-child transmission.
- 75% of children presented in advanced or severe clinical stages of the disease.
- 56.8% of the children had severe immunodeficiency.
Takeaway
This study looked at how many kids in Nigeria have HIV and found that a lot of them got it from their moms. Many of these kids are very sick when they find out.
Methodology
A prospective cross-sectional study using provider initiated HIV testing and counselling (PITC) model with HIV rapid tests and confirmatory tests.
Potential Biases
The study site being a referral center may have contributed to the high prevalence observed.
Limitations
The study did not capture data on HIV exposed infants under 6 weeks old and those still breastfeeding, which may require further testing.
Participant Demographics
Children aged less than 15 years, with a male to female ratio of 1.2:1.
Statistical Information
P-Value
0.000
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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