Study Protocol for Pregnancy Outcome Prediction
Author Information
Author(s): Pasupathy Dharmintra, Dacey Alison, Cook Emma, Charnock-Jones D Stephen, White Ian R, Smith Gordon CS
Primary Institution: Department of Obstetrics and Gynaecology, University of Cambridge
Hypothesis
Can clinically useful methods be developed to screen women for adverse pregnancy outcomes?
Conclusion
The study aims to identify novel biomarkers for adverse pregnancy outcomes and evaluate the effectiveness of these biomarkers and serial ultrasonography in predicting risks.
Supporting Evidence
- The study aims to recruit 4000 women to ensure adequate data for analysis.
- It focuses on primiparous women to better understand risks associated with their pregnancies.
- The study design includes multiple data collection points throughout pregnancy.
Takeaway
This study is trying to find better ways to check if pregnant women might have problems with their babies by using tests and scans.
Methodology
The study involves recruiting primiparous women for serial phlebotomy and ultrasounds at various stages of pregnancy to collect data and samples.
Potential Biases
Potential bias may arise from the self-reported data and the specific demographic of primiparous women.
Limitations
The study is limited to a single center initially and may not generalize to other populations.
Participant Demographics
Primiparous women with singleton pregnancies attending for their dating scan.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website