Identification and characterisation of the high-risk surgical population in the United Kingdom
2006

High-Risk Surgical Population in the UK

Sample size: 4117727 publication Evidence: high

Author Information

Author(s): Rupert M Pearse, David A Harrison, Philip James, David Watson, Charles Hinds, Andrew Rhodes, R Michael Grounds, E David Bennett

Primary Institution: William Harvey Research Institute, Queen Mary's School of Medicine and Dentistry, London, UK

Hypothesis

What proportion of general surgical patients are at high risk of postoperative death?

Conclusion

A large high-risk surgical population accounts for 12.5% of surgical procedures but for more than 80% of deaths.

Supporting Evidence

  • The high-risk surgical population identified accounted for 83.8% of deaths but only 12.5% of procedures.
  • Among ICU admissions, 40.8% of deaths occurred after initial discharge from the ICU.
  • The highest mortality rate was 39% in patients admitted to the ICU following initial postoperative care on a standard ward.

Takeaway

There are many patients who are at high risk of dying after surgery, and they make up a small part of all surgeries but a big part of the deaths.

Methodology

Data on inpatient general surgical procedures and ICU admissions were extracted from two healthcare databases for 94 NHS hospitals over a period of approximately 5 years.

Potential Biases

Potential underestimation of mortality rates due to limitations in coding and data collection methods.

Limitations

The study relies on data from large healthcare databases, which may not capture all relevant mortality data accurately.

Participant Demographics

Median age of patients was 56 years, with 43% male in the general surgical population.

Statistical Information

P-Value

p<0.0001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/cc4928

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