Prevalence and Risk Factors of Human Papillomavirus (HPV) Infection in Southern Chinese Women – A Population-Based Study
2011

HPV Prevalence in Southern China

Sample size: 2940 publication 10 minutes Evidence: high

Author Information

Author(s): Liu Stephanie Si, Chan Kelvin Yuen Kwong, Leung Rebecca Ching Yu, Chan Karen Kar Loen, Tam Kar Fai, Luk May Hiu Mei, Lo Sue Seen Tsing, Fong Daniel Yee Tak, Cheung Annie Nga Yin, Lin Zhong Qiu, Ngan Hextan Yuen Sheung

Primary Institution: The University of Hong Kong

Hypothesis

This study aimed to compare the HPV prevalence and risk factors between women residing in Hong Kong and Guangzhou.

Conclusion

The study found that HPV prevalence is significantly higher in women from Guangzhou compared to those from Hong Kong.

Supporting Evidence

  • HPV prevalence in the GZ cohort was 10%, significantly higher than 6.2% in the HK cohort.
  • Women in the GZ cohort had a higher prevalence of high-risk HPV types compared to those in HK.
  • Age was a significant risk factor for HPV infection in the HK cohort.

Takeaway

The study looked at how many women in Hong Kong and Guangzhou have HPV, a virus that can cause cervical cancer, and found more women in Guangzhou have it.

Methodology

A cross-sectional study was conducted with cytology samples collected from women in both regions, and HPV detection was performed.

Potential Biases

Potential bias due to differences in cervical screening programs between the two regions.

Limitations

The study only included women with normal cytology and did not account for sexual behavior details of partners.

Participant Demographics

Women aged 20 and older from Hong Kong and Guangzhou, with varying education levels and sexual histories.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI: 5.1–7.3% for HK and 95% CI: 8.4–11.5% for GZ

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1371/journal.pone.0019244

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