Treatment selection and influencing factors for chronic lymphocytic leukemia: a physician survey in Japan
2024

Treatment Choices for Chronic Lymphocytic Leukemia in Japan

Sample size: 107 publication 10 minutes Evidence: moderate

Author Information

Author(s): Yuda Junichiro, Wang Chaochen, Terasawa Tomoko, Tajimi Masaomi, Osaga Satoshi, Miura Moemi, Takaoka Shori, Tanizawa Yoshinori

Primary Institution: National Cancer Center Hospital East

Hypothesis

What factors influence hematologists' treatment decisions for chronic lymphocytic leukemia (CLL) in Japan?

Conclusion

Japanese hematologists often choose treatments based on clinical evidence, but there are variations influenced by their experience and interest in CLL.

Supporting Evidence

  • 82.2% of hematologists preferred BTK inhibitors as the first-line treatment for CLL.
  • Key factors influencing treatment selection included clinical evidence and patient fitness status.
  • Variations in treatment choices were noted based on the hematologists' experience and interest in CLL.

Takeaway

Doctors in Japan mostly pick a specific medicine for a type of blood cancer called CLL based on what they know and how long they've been working.

Methodology

An online survey was conducted among hematologists treating CLL, with responses analyzed descriptively.

Potential Biases

Potential bias due to self-disclosed participant backgrounds and limited exposure to CLL treatment options.

Limitations

The study relied on self-reported data and did not conduct statistical testing for variations in attitudes.

Participant Demographics

The sample included 107 hematologists, with 76.6% being certified specialists and 74.8% having at least 10 years of clinical experience.

Digital Object Identifier (DOI)

10.1007/s10147-024-02645-6

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