Novel Human Rhinoviruses and Asthma in Children
Author Information
Author(s): Khetsuriani Nino, Lu Xiaoyan, Teague W. Gerald, Kazerouni Neely, Anderson Larry J., Erdman Dean D.
Primary Institution: Centers for Disease Control and Prevention
Hypothesis
To determine links between human rhinoviruses (HRV) and asthma.
Conclusion
The study found that asthma exacerbations were largely driven by novel genogroup C HRVs and species A.
Supporting Evidence
- HRVs were detected in 37% of children with asthma.
- The association of asthma exacerbations with HRV infection was statistically significant for species A and genogroup C.
- Patients infected with genogroup C HRVs had lower forced expiratory volumes than those infected with other HRVs.
Takeaway
This study shows that some new types of viruses can make kids with asthma feel worse, especially a group called genogroup C.
Methodology
A case-control study was conducted among children with asthma, using molecular characterization methods to identify HRVs.
Limitations
The study may not account for all variables affecting asthma exacerbations.
Participant Demographics
Children with asthma aged over 2 years.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI 1.9–43.1
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website