KI and WU Polyomaviruses in Children, France
2008

KI and WU Polyomaviruses in Children, France

Sample size: 537 publication Evidence: low

Author Information

Author(s): Foulongne Vincent, Brieu Natalie, Jeziorski Eric, Chatain Amandine, Rodière Michel, Segondy Michel

Primary Institution: Montpellier University Hospital

Conclusion

The study found that KI and WU polyomaviruses were detected in a small percentage of children with respiratory tract disease, but their clinical relevance remains uncertain.

Supporting Evidence

  • WUPyV was detected in 2.4% of children under 5 years of age with respiratory tract disease.
  • KIPyV was detected in 0.6% of boys in the study.
  • All children infected with WUPyV and KIPyV recovered within 1 to 10 days, except one child with congenital myopathy.

Takeaway

Researchers looked at sick kids and found some had new viruses, but it's not clear if those viruses made them sick.

Methodology

Nasopharyngeal aspirates were collected from children and tested for various viruses using PCR and other assays.

Potential Biases

High rates of co-infection raise questions about the pathogenic role of the polyomaviruses.

Limitations

The study only tested symptomatic children and did not include asymptomatic controls.

Participant Demographics

Children under 5 years of age with acute respiratory tract disease.

Digital Object Identifier (DOI)

10.3201/eid1403.071206

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication