Potentials of leaves of Aspilia africana (Compositae) in wound care: an experimental evaluation
2007
Using Aspilia africana Leaves for Wound Care
Sample size: 30
publication
10 minutes
Evidence: moderate
Author Information
Author(s): Okoli CO, Akah PA, Okoli AS
Primary Institution: University of Nigeria, Nsukka
Hypothesis
The leaves of Aspilia africana can be effective in wound care.
Conclusion
The leaves of A. africana can stop bleeding, inhibit microbial growth, and speed up wound healing.
Supporting Evidence
- The extract significantly reduced bleeding/clotting time in rats.
- The methanol fraction showed the highest antimicrobial activity against wound contaminants.
- The leaves accelerated the epithelialisation period of wounds in rats.
Takeaway
The leaves of a plant called Aspilia africana can help heal wounds by stopping bleeding and fighting germs.
Methodology
The study involved extracting compounds from the leaves and testing their effects on bleeding time, coagulation time, microbial growth, and wound healing in rats.
Participant Demographics
Adult Swiss albino mice and rats of both sexes were used.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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