Survival Analysis Part II: Multivariate data analysis – an introduction to concepts and methods
2003

Survival Analysis Part II: Multivariate Data Analysis

publication Evidence: high

Author Information

Author(s): Bradburn M J, Clark T G, Love S B, Altman D G

Primary Institution: Cancer Research UK/NHS Centre for Statistics in Medicine

Conclusion

Statistical models, particularly the Cox model, are essential for analyzing survival data by considering multiple factors simultaneously.

Supporting Evidence

  • Higher FIGO stage and grade impair survival.
  • Presence of ascites negatively affects survival.
  • Age increases the hazard of the event.

Takeaway

This study explains how to analyze survival data, which is important for understanding how different factors affect how long patients live after a diagnosis.

Methodology

The paper discusses various statistical models for survival analysis, including the Cox proportional hazards model and accelerated failure time models.

Limitations

The choice of covariates to include in the model can be complex, and the proportional hazards assumption may not always hold.

Statistical Information

P-Value

<0.001

Confidence Interval

(1.82–2.37)

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1038/sj.bjc.6601119

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