Evolution of GHF5 endoglucanase gene structure in plant-parasitic nematodes: no evidence for an early domain shuffling event
2008

Evolution of GHF5 Endoglucanase Genes in Nematodes

publication Evidence: moderate

Author Information

Author(s): Kyndt Tina, Haegeman Annelies, Gheysen Godelieve

Primary Institution: Department of Molecular Biotechnology, Ghent University

Hypothesis

The study investigates whether the ancestral GHF5 endoglucanase gene in plant-parasitic nematodes evolved through domain shuffling or consisted of a complete gene cassette.

Conclusion

The ancestral PPN GHF5 endoglucanase gene most likely consisted of the whole gene cassette, rather than evolving by domain shuffling.

Supporting Evidence

  • The study included new data from migratory nematodes.
  • Phylogenetic analyses showed no statistical incongruence between the catalytic domain and the carbohydrate-binding module.
  • The research confirmed a close relationship between Pratylenchus spp. and root knot nematodes.

Takeaway

Scientists studied genes from nematodes to see how they evolved. They found that these genes likely came from a complete set of instructions, not from mixing parts of different genes.

Methodology

Phylogenetic analyses were conducted using sequences from various nematodes and other organisms to study the evolution of GHF5 endoglucanases.

Limitations

The study primarily focused on specific nematode species and may not represent all plant-parasitic nematodes.

Digital Object Identifier (DOI)

10.1186/1471-2148-8-305

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