Association Between COVID-19 and Orthostatic Intolerance in Children: A Retrospective Study
2024

COVID-19 and Orthostatic Intolerance in Children

Sample size: 16 publication Evidence: low

Author Information

Author(s): Muacevic Alexander, Adler John R, Kakavand Bahram, Centner Safia, Centner Aliya

Primary Institution: Nemours Children's Health System, Orlando, USA

Hypothesis

This study aims to evaluate the clinical and laboratory findings in pediatric patients with post-COVID-19 or post-COVID-19 vaccine orthostatic intolerance and postural orthostatic tachycardia syndrome.

Conclusion

The study highlights the increasing incidence of POTS and other forms of orthostatic intolerance in children following COVID-19 infection and vaccination.

Supporting Evidence

  • 62.5% of patients met the criteria for POTS.
  • Mean standing norepinephrine levels were 520 pg/mL.
  • 43.75% of patients showed abnormal results on the Valsalva maneuver.
  • 50% of those who underwent QSART demonstrated small fiber neuropathy.

Takeaway

Some kids can feel dizzy and have fast heart rates after getting COVID-19 or the vaccine, and this study looked at how common that is.

Methodology

This was a retrospective chart review of pediatric patients under 18 years with chronic dizziness or syncope following COVID-19 infection or vaccination, including autonomic studies.

Limitations

The study has a small sample size and lacks long-term outcome data.

Participant Demographics

16 patients (15 female, 1 male) with a mean age of 15 ± 3 years.

Digital Object Identifier (DOI)

10.7759/cureus.74857

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