Chronic Diarrhea and Pancolitis from Fungal Coinfection
Author Information
Author(s): Eduar A. Bravo, Arturo J. Zegarra, Alejandro Piscoya, José L. Pinto, Raúl E. de los Rios, Ricardo A. Prochazka, Jorge L. Huerta-Mercado, Jaime Cok, Martin Tagle
Primary Institution: Hospital Nacional Cayetano Heredia
Hypothesis
Can dimorphic fungal coinfection cause chronic diarrhea and pancolitis?
Conclusion
The case illustrates a rare instance of chronic diarrhea and pancolitis caused by a coinfection of two dimorphic fungi.
Supporting Evidence
- Histoplasma capsulatum and Paracoccidioides brasiliensis are known to cause systemic mycosis.
- Colonic fungal infection is rare and often associated with multisystem disease.
- The patient had a good clinical response to treatment with amphotericin B.
Takeaway
A man had severe diarrhea and stomach problems because of two types of fungi infecting him at the same time, which is very unusual.
Methodology
The patient was evaluated through clinical examination, blood tests, colonoscopy, and histopathological analysis.
Potential Biases
Potential bias in diagnosis due to the rarity of the condition.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
34-year-old male from Chanchamayo, Junin, Peru.
Digital Object Identifier (DOI)
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