CMV retinitis screening and treatment in a resource-poor setting: three-year experience from a primary care HIV/AIDS programme in Myanmar
2011

CMV Retinitis Management in Myanmar

Sample size: 891 publication Evidence: moderate

Author Information

Author(s): Tun Ni, London Nikolas, Kyaw Moe Kyaw, Smithuis Frank, Ford Nathan, Margolis Todd, Drew W Lawrence, Lewallen Susan, Heiden David

Primary Institution: Medical Action Myanmar

Hypothesis

Can non-ophthalmologists effectively manage CMV retinitis in resource-poor settings?

Conclusion

CMV retinitis can be effectively diagnosed and treated by trained AIDS clinicians in resource-poor settings.

Supporting Evidence

  • CMV retinitis was diagnosed in 24% of new patients screened.
  • A total of 1296 injections of ganciclovir were administered.
  • Training improved the ability of AIDS clinicians to diagnose CMV retinitis.

Takeaway

Doctors who treat HIV can learn to check for and treat a serious eye disease called CMV retinitis, helping patients avoid blindness.

Methodology

Retrospective descriptive study involving training of AIDS clinicians and systematic screening of high-risk patients.

Potential Biases

Potential bias due to reliance on non-ophthalmologists for diagnosis and treatment.

Limitations

Some clinical events may have been missed due to missed appointments or unrecorded events.

Participant Demographics

Majority of patients were male (64.3%), median age was 32 years, and median CD4 cell count was 38 cells/mm3.

Digital Object Identifier (DOI)

10.1186/1758-2652-14-41

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