BKM-react: A New Biochemical Reaction Database
Author Information
Author(s): Lang Maren, Stelzer Michael, Schomburg Dietmar
Primary Institution: Technische Universität Braunschweig
Hypothesis
An integrated knowledge resource for biochemical reactions can enhance the reconstruction of metabolic networks.
Conclusion
The developed integrated non-redundant reaction database can significantly facilitate and accelerate the construction of accurate biochemical models.
Supporting Evidence
- The database contains 18,172 unique biochemical reactions.
- It integrates data from three major biochemical databases: BRENDA, KEGG, and MetaCyc.
- The tool allows for the construction of more complete biological models.
Takeaway
Scientists created a big database that combines information about chemical reactions from different sources, making it easier to study how living things work.
Methodology
The database was created by integrating data from BRENDA, KEGG, and MetaCyc using a two-step comparison of reaction structures and names.
Limitations
The database may not include all reactions due to differences in naming and structural representation across source databases.
Digital Object Identifier (DOI)
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