Reirradiation and Hyperthermia for Breast Cancer
Author Information
Author(s): Zee J van der, Holt B van der, Rietveld P J M, Helle P A, Wijnmaalen A J, Putten W L J van, Rhoon G C van
Primary Institution: University Hospital Rotterdam, Daniel den Hoed Cancer Center
Hypothesis
Does reirradiation combined with hyperthermia provide effective local palliation in recurrent breast cancer?
Conclusion
The study found that reirradiation combined with hyperthermia resulted in a high local control rate and acceptable toxicity in patients with recurrent breast cancer.
Supporting Evidence
- The complete response rate in patients with macroscopic tumor was 71%.
- The local control rate was 73% when including patients with microscopic disease.
- The median duration of local control was 32 months.
- Toxicity was acceptable for the treatment regimen.
Takeaway
This study shows that using heat along with radiation can help control breast cancer that comes back, and most patients tolerate it well.
Methodology
Patients with recurrent breast cancer were treated with reirradiation and hyperthermia, and their responses were evaluated.
Digital Object Identifier (DOI)
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