(1E,4E)-1,5-Bis(2,4,6-trimethoxyphenyl)penta-1,4-dien-3-one
2011
(1E,4E)-1,5-Bis(2,4,6-trimethoxyphenyl)penta-1,4-dien-3-one Crystal Structure
publication
Evidence: moderate
Author Information
Author(s): Ruanwas Pumsak, Chantrapromma Suchada, Fun Hoong-Kun
Primary Institution: Prince of Songkla University
Hypothesis
The study aims to investigate the effect of the positions of the trimethoxy substituents on the fluorescence property and anti-tyrosinase activity of the synthesized bischalcone.
Conclusion
The title bischalcone possesses anti-tyrosinase activity and its crystal structure has been successfully determined.
Supporting Evidence
- The synthesized bischalcone was tested for anti-tyrosinase activity.
- The crystal structure revealed two independent molecules with slight differences.
- The molecular structure is almost planar with specific dihedral angles between benzene rings.
- Weak intermolecular interactions stabilize the crystal structure.
Takeaway
Scientists made a new chemical compound and found out that it can help stop a certain process in the body that causes skin darkening.
Methodology
The compound was synthesized and its crystal structure was analyzed using X-ray crystallography.
Digital Object Identifier (DOI)
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