Cortical Activations in Humans Grasp-Related Areas Depend on Hand Used and Handedness
2008

How Handedness Affects Brain Activity During Grasping

Sample size: 34 publication 10 minutes Evidence: moderate

Author Information

Author(s): Begliomini Chiara, Nelini Cristian, Caria Andrea, Grodd Wolfgang, Castiello Umberto

Primary Institution: Department of General Psychology, University of Padua, Padua, Italy

Hypothesis

Does handedness influence the neural activity in grasp-related brain areas during precision grip tasks?

Conclusion

The study found that neural activity in grasp-related areas varies depending on the hand used and the individual's handedness.

Supporting Evidence

  • Right- and left-handers showed different patterns of brain activation when using their non-dominant hand.
  • Significant activity was found in the right dorsal premotor cortex during grasping tasks.
  • Bilateral activation in the anterior intraparietal sulcus was observed regardless of handedness.

Takeaway

This study shows that whether you are right or left-handed can change how your brain works when you grab things.

Methodology

Functional magnetic resonance imaging (fMRI) was used to measure brain activity while participants performed precision grip tasks with either hand.

Potential Biases

Potential biases may arise from the small sample size and the specific demographic of participants.

Limitations

The study primarily focused on right- and left-handed individuals, which may limit the generalizability of the findings to other populations.

Participant Demographics

Nineteen right-handed (12 women, 7 men) and fifteen left-handed (10 women, 5 men) participants were included.

Statistical Information

P-Value

p<0.0001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0003388

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