Mapping Genetic Resistance to Coccidiosis in Chickens
Author Information
Author(s): Pinard-van der Laan Marie-Hélène, Bed'hom Bertrand, Coville Jean-Luc, Pitel Frédérique, Feve Katia, Leroux Sophie, Legros Hélène, Thomas Aurélie, Gourichon David, Repérant Jean-Michel, Rault Paul
Primary Institution: INRA/AgroParisTech, UMR1236 Génétique et Diversité Animales
Hypothesis
Can we identify quantitative trait loci (QTL) for resistance to Eimeria tenella in chickens?
Conclusion
The study successfully identified multiple QTL associated with resistance traits to Eimeria tenella, paving the way for future breeding strategies.
Supporting Evidence
- The QTL analysis detected 21 chromosome-wide significant QTL for various resistance traits.
- A genome-wide very significant QTL for body weight growth was found on GGA1.
- Parent-of-origin effects were identified for QTL related to body weight growth and plasma coloration.
- The study suggests several candidate genes linked to immune responses.
Takeaway
Scientists found specific genes in chickens that help them fight a disease caused by a parasite, which could help breed healthier chickens in the future.
Methodology
The study used an F2 cross from resistant Fayoumi and susceptible Leghorn chicken lines to perform a genome scan for QTL.
Limitations
The study did not include mortality data due to low levels of mortality in the F2 population.
Participant Demographics
The study involved chickens from two distinct lines: Fayoumi (resistant) and Leghorn (susceptible).
Statistical Information
P-Value
P < 0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website