Polyphosphate - an ancient energy source and active metabolic regulator
2011

Polyphosphate: An Ancient Energy Source and Active Metabolic Regulator

publication

Author Information

Author(s): Achbergerová Lucia, Nahálka Jozef

Primary Institution: Slovak Academy of Sciences

Hypothesis

Polyphosphate and calcium-rich organelles have endosymbiotic origins from ancient protocells that metabolized polyphosphate.

Conclusion

Inorganic polyphosphate is a molecule of many functions involved in energetic metabolism and gene regulation.

Supporting Evidence

  • Polyphosphate is found in every type of cell in nature.
  • Polyphosphate plays a central role in the stress response of microorganisms.
  • Polyphosphate kinases are key enzymes that mediate the synthesis and degradation of polyphosphate chains.

Takeaway

Polyphosphate is a special molecule that helps cells store energy and control important processes, and it has been around since the early days of life on Earth.

Digital Object Identifier (DOI)

10.1186/1475-2859-10-63

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