Long-Term Outcomes for Elderly Patients with Aortic Stenosis
Author Information
Author(s): Esposito Augusto, Foffa Ilenia, Quadrelli Paola, Bastiani Luca, Vecoli Cecilia, Del Turco Serena, Berti Sergio, Mazzone Annamaria
Primary Institution: Cardiology Unit, Ospedale del Cuore, Fondazione Toscana “G. Monasterio”
Hypothesis
Can frailty-based management improve survival and quality of life in elderly patients with severe aortic stenosis over six years?
Conclusion
Elderly patients with severe aortic stenosis benefit from tailored interventional treatment based on frailty assessment, showing improved survival and functional status over six years.
Supporting Evidence
- At six years, the survival rate was 40%, higher in pre-frail patients.
- Patients who underwent TAVR had a significantly better survival rate.
- The FIMS score was an independent predictor of mortality.
- Functional status declined moderately but significantly over six years.
Takeaway
Older people with a serious heart condition can live longer and feel better if doctors consider their overall health and frailty when deciding on treatment.
Methodology
The study evaluated 109 elderly patients with severe aortic stenosis using a frailty-based management approach and assessed outcomes over six years.
Potential Biases
Self-reported functional status may not have been validated against objective measures.
Limitations
The study is retrospective and has a limited sample size.
Participant Demographics
Median age 83.3 years, 32% male.
Statistical Information
P-Value
0.001
Confidence Interval
1.7–5.1
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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