Anti-inflammatory treatment of childhood asthma: cromoglycate and nedocromil as non-steroidal alternatives?
1994
Non-steroidal Treatments for Childhood Asthma
publication
Evidence: moderate
Author Information
Author(s): Johar C. de Jongste
Primary Institution: Erasmus University and University Hospital/Sophia Children's Hospital
Hypothesis
Can non-steroidal anti-inflammatory drugs like cromoglycate and nedocromil effectively treat childhood asthma without the side effects of corticosteroids?
Conclusion
Cromoglycate is effective and safe for treating moderate childhood asthma, while nedocromil shows promise but requires further study.
Supporting Evidence
- Cromoglycate has been used for many years and is proven to be effective and safe.
- Nedocromil is more potent than cromoglycate but lacks sufficient data to confirm its superiority.
- The benefits of inhaled corticosteroids are generally considered to outweigh their risks.
Takeaway
This study looks at two asthma medicines that don't use steroids, which can be safer for kids. One medicine is already known to work well, while the other needs more testing.
Limitations
Limited data on the effectiveness of nedocromil in children.
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